| 2022-03-20 13:00:0020th March 2022 | Sefton vs Cheltenham Tigers Women’s XV | 13:00:001:00 pm | Away | Recap |
| 2022-03-12 14:45:0012th March 2022 | Cheltenham Tigers Women’s XV vs Barnsley | 14:45:002:45 pm | Newlands Park | Recap |
| 2022-02-26 13:00:0026th February 2022 | West Park Leeds vs Cheltenham Tigers Women’s XV | 13:00:001:00 pm | Away | Recap |
| 2022-02-19 14:30:0019th February 2022 | Cheltenham Tigers Women’s XV vs Harrogate | 69 - 10 | Newlands Park | Recap |
| 2022-02-13 14:30:0013th February 2022 | Cheltenham Tigers Women’s XV vs Novocastrians | 74 - 0 | Newlands Park | Recap |
| 2022-02-05 13:00:005th February 2022 | Firwood W’loo vs Cheltenham Tigers Women’s XV | 0 - 33 | Away | Recap |
| 2022-01-29 14:00:0029th January 2022 | Cheltenham Tigers Women’s XV vs Lichfield | 49 - 10 | Newlands Park | Recap |
| 2022-01-23 14:00:0023rd January 2022 | Cheltenham Tigers Women’s XV vs West Park Leeds | 59 - 7 | Newlands Park | Recap |
| 2022-01-16 13:00:0016th January 2022 | Loughborough vs Cheltenham Tigers Women’s XV | 0 - 31 | Away | Recap |
| 2022-01-08 13:00:008th January 2022 | Kenilworth vs Cheltenham Tigers Women’s XV | 0 - 38 | Away | Recap |
| 2021-12-18 13:00:0018th December 2021 | Cheltenham Tigers Women’s XV vs Novocastrians | 13:00:001:00 pm | Newlands Park | Recap |
| 2021-12-11 13:00:0011th December 2021 | Barnsley vs Cheltenham Tigers Women’s XV | 13:00:001:00 pm | Away | Recap |
| 2021-11-27 14:00:0027th November 2021 | Cheltenham Tigers Women’s XV vs West Park Leeds | 14:00:002:00 pm | Newlands Park | Recap |
| 2021-11-20 13:00:0020th November 2021 | Harrogate vs Cheltenham Tigers Women’s XV | 13:00:001:00 pm | Away | Recap |
| 2021-11-13 15:30:0013th November 2021 | Cheltenham Tigers Women’s XV vs Firwood W'Loo | 15:30:003:30 pm | Newlands Park | Recap |
| 2021-10-30 13:00:0030th October 2021 | Lichfield vs Cheltenham Tigers Women’s XV | 13:00:001:00 pm | Away | Recap |
| 2021-10-24 14:30:0024th October 2021 | Cheltenham Tigers Women’s XV vs Loughborough | 14:30:002:30 pm | Newlands Park | Recap |
| 2021-10-16 13:00:0016th October 2021 | Cheltenham Tigers Women’s XV vs Kenilworth | 13:00:001:00 pm | Newlands Park | Recap |
| 2021-10-02 13:00:002nd October 2021 | Novocastrians vs Cheltenham Tigers Women’s XV | 13:00:001:00 pm | Away | Recap |
| 2021-09-26 13:00:0026th September 2021 | Cheltenham Tigers Women’s XV vs Sefton | 13:00:001:00 pm | Newlands Park | Recap |
| 2021-08-21 13:00:0021st August 2021 | Cheltenham Tigers Women’s XV vs Reading Abbey | 13:00:001:00 pm | Newlands Park | Recap |
